abstract：OBJECTIVES:Oral lichen planus is a chronic, T-cell-mediated, inflammatory disease that affects the oral cavity. The oral lichen planus pathogenesis is still unclear, however, the main evidence is that the mechanisms of activation of different T lymphocyte pathway induce apoptosis with an increase in Th1 and Th17 subtyp...

journal_title：Oral diseases

authors： Souza MM,Florezi GP,Nico M,de Paula F,Paula FM,Lourenço SV

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:This study aimed to analyse Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) viral loads in symptomatic and asymptomatic apical periodontitis lesions, to determine levels of TNF-α, IL-1β and IL-6 in these lesions and to investigate a possible correlation between herpesviral copy numbers and levels o...

journal_title：Oral diseases

authors： Jakovljevic A,Knezevic A,Nikolic N,Soldatovic I,Jovanovic T,Milasin J,Andric M

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:To comparatively assess periodontal status in patients who chew different products and patients who do not have this habit and to assess how this practice interacts with predisposing factors and risk indicators of disease. METHODS:Patients included in the dental care carried out in a rural community in Indi...

journal_title：Oral diseases

authors： Giovannoni ML,Valdivia-Gandur I,Lozano de Luaces V,Varela Véliz H,Balasubbaiah Y,Chimenos-Küstner E

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To study the incidence and magnitude of bacteremia after dental extraction and supragingival scaling. SUBJECTS AND METHODS:Blood samples were taken before and 5 and 30 min after dental extraction and supragingival scaling from individuals at high (n = 44) or negligible risk (n = 51) for infective endocarditi...

journal_title：Oral diseases

authors： Reis LC,Rôças IN,Siqueira JF Jr,de Uzeda M,Lacerda VS,Domingues R,Miranda KR,Saraiva RM

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To evaluate whether the oral functionality and the oral sensorimotor alterations are associated with oropharyngeal dysphagia in community-dwelling older persons and long-term care older residents. METHODS:An exploratory study with 265 independent older persons of the southern state of Brazil. The diagnosis o...

journal_title：Oral diseases

authors： Rech RS,Baumgarten A,Colvara BC,Brochier CW,de Goulart B,Hugo FN,Hilgert JB

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To investigate the therapeutic effect of oral glucosamine (GS) as an adjunct to hyaluronic acid (HA) injection on patients with temporomandibular joint osteoarthritis (TMJ OA). METHODS:In this clinical trial, 136 participants, diagnosed as TMJ OA clinically and radiographically, were enrolled and randomized ...

journal_title：Oral diseases

authors： Cen X,Liu Y,Wang S,Yang X,Shi Z,Liang X

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:To propose the application of the concept of geriatric syndrome for common geriatric oral and maxillofacial dysfunctions and to suggest the necessity of developing effective evaluation methods for oral and maxillofacial frailty. DESIGN:The concepts of frailty and geriatric syndrome based on multi-morbidity ...

journal_title：Oral diseases

authors： Nam Y,Kim NH,Kho HS

更新日期：2018-04-01 00:00:00

abstract：:The clinical presentation of oral lichen planus and oral lichenoid lesions is diverse. A special category of patients presents with lichenoid lesions affecting only the mucosa of their upper lip and the anterior upper gingiva. This is a concise review summarizing the specific characteristics of these patients. ...

journal_title：Oral diseases

authors： Georgakopoulou EA,Malamos D,Achtari MD

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:Clastic cells, originating from the monocyte-macrophage lineage, resorb mineralized tissues. In periapical periodontitis, alveolar bone around the tooth apex becomes resorbed; however, the roots of the teeth are often left intact by yet unknown mechanisms. Here, we examined the status of clastic cells in a...

journal_title：Oral diseases

authors： Shah A,Lee D,Song M,Kim S,Kang MK,Kim RH

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To generate a nomogram for predicting the risk of neck node metastasis in pathologically node-negative patients using a combination of variables comprising of protein expression, ultrastructural alterations and clinicopathological parameters. MATERIALS AND METHODS:Surgically removed oral tumours (n = 103) we...

journal_title：Oral diseases

authors： Sawant SS,Dongre H,Ahire C,Sharma S,Kannan S,Mahadik S,Chaukar D,Lukmani F,Patil A,D'Cruz A,Vaidya MM,Dongre P

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To examine oral complications 6 months after modern radiation therapy (RT) for head and neck cancer (HNC). METHODS:Prospective multicenter cohort study of patients with HNC receiving intensity-modulated radiation therapy or more advanced RT. Stimulated whole salivary flow, maximal mouth opening, oral mucosit...

journal_title：Oral diseases

authors： Lalla RV,Treister N,Sollecito T,Schmidt B,Patton LL,Mohammadi K,Hodges JS,Brennan MT,OraRad Study Group.

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To describe the clinical and genetic features of patients with cherubism. MATERIAL AND METHODS:A descriptive analysis of 14 cases from nine different families was carried out. Clinicopathological, imaging, and follow-up data were retrieved from patients' medical files and correlated with the genetic profile ...

journal_title：Oral diseases

authors： Machado RA,Pontes H,Pires FR,Silveira HM,Bufalino A,Carlos R,Tuji FM,Alves D,Santos-Silva AR,Lopes MA,Capistrano HM,Coletta RD,Fonseca FP

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:The association between body mass index (BMI) and oral diseases was investigated, and levels of obesity-related inflammatory mediators were evaluated. SUBJECTS AND METHODS:Participants (n = 160) were clinically and radiographically examined for oral diseases. Blood profiles were recorded. Levels of adiponec...

journal_title：Oral diseases

authors： Thanakun S,Pornprasertsuk-Damrongsri S,Izumi Y

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To assess changes in the salivary expression of IL-1α, IL-1β, IL-2, IL-6, IL-10, IL-17, and TNF in acute leukemia (AL) patients before and during chemotherapy, and its association with HSV infection, oral candidiasis (OC), and oral mucositis (OM) onset. METHODS:Cohort study in AL patients >15 years starting ...

journal_title：Oral diseases

authors： Ramírez-Amador V,Zambrano JG,Anaya-Saavedra G,Zentella-Dehesa A,Irigoyen-Camacho E,Meráz-Cruz N,Ponce de León-Rosales S

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:The access to probiotics should be facilitated in order to encourage their usage. We evaluated the effect of consumption of two experimental probiotic-containing cheeses on the oral colonization of Candida in denture wearers. METHODS:Sixty denture wearers harboring oral Candida were randomly allocated in gr...

journal_title：Oral diseases

authors： Miyazima TY,Ishikawa KH,Mayer M,Saad S,Nakamae A

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:Fourier Transform Infrared microspectroscopy let characterize the macromolecular composition and distribution of tissues and cells, by studying the interaction between infrared radiation and matter. Therefore, we hypothesize to exploit this analytical tool in the analysis of inflamed pulps, to detect the dif...

journal_title：Oral diseases

authors： Giorgini E,Sabbatini S,Conti C,Rubini C,Rocchetti R,Fioroni M,Memè L,Orilisi G

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Cathepsin K was initially discovered as an osteoclast-specific cysteine proteinase, but the enzyme is also expressed in various cancers including oral squamous cell carcinomas. This study aimed to clarify the function of cathepsin K in oral squamous cell carcinomas. MATERIALS AND METHODS:Expression levels of...

journal_title：Oral diseases

authors： Yamashita K,Iwatake M,Okamoto K,Yamada SI,Umeda M,Tsukuba T

更新日期：2017-05-01 00:00:00

abstract：:Periodontal diseases, primarily gingivitis and periodontitis, are characterised by progressive inflammation and tissue destruction. However, they are unusual in that they are not also accompanied by the pain commonly seen in other inflammatory conditions. This suggests that interactions between periodontal bacteria an...

journal_title：Oral diseases

authors： Gaurilcikaite E,Renton T,Grant AD

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To compare counts of Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Porphyromonas gingivalis and Fusobacterium nucleatum between crack users and non-users. MATERIALS AND METHODS:A cross-sectional study was conducted involving seventy-four crack cocaine users and eighty-one non-users matched fo...

journal_title：Oral diseases

authors： Casarin M,Antoniazzi RP,Vaucher RA,Feldens CA,Zanatta FB

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:In this study, we aimed to clarify the precise mechanism underlying lipopolysaccharide (LPS)-induced osteoclastogenesis in periodontal disease with a special reference to double-stranded RNA-dependent protein kinase (PKR). MATERIAL AND METHODS:We dissected the role of PKR in LPS-induced osteoclast differenti...

journal_title：Oral diseases

authors： Teramachi J,Inagaki Y,Shinohara H,Okamura H,Yang D,Ochiai K,Baba R,Morimoto H,Nagata T,Haneji T

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Both an elevated leukocyte count and periodontitis share well-recognized associations with cardiometabolic diseases. This cross-sectional study aimed to identify whether the leukocyte count is associated with periodontitis in a nationally representative Korean adult population. MATERIALS AND METHODS:Data fro...

journal_title：Oral diseases

authors： Kwon YJ,Jeon KJ,Chung TH,Lee YJ

更新日期：2017-03-01 00:00:00

abstract：:Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this condition. In addition to evidence regarding the basic and clinic...

journal_title：Oral diseases

authors： Ceponis P,Keilman C,Guerry C,Freiberger JJ

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Bisphosphonates are widely used to treat bone diseases such as osteoporosis. However, they may cause osteonecrosis of the jaw. Here, we investigated whether in vivo exposure to bisphosphonates has a different effect on long bone and jaw osteoclasts, and on the turnover of these different bones. MATERIALS AN...

journal_title：Oral diseases

authors： Vermeer J,Renders G,van Duin MA,Jansen I,Bakker LF,Kroon SA,de Vries TJ,Everts V

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Periodontal and cardiovascular diseases share some common underlying mechanisms. Hyperlipidemia is a major risk factor for cardiovascular diseases. This study sought to assess the association of hyperlipidemia and statin consumption with periodontal status. MATERIALS AND METHODS:This cross-sectional study w...

journal_title：Oral diseases

authors： Sayar F,Fallah S,Akhondi N,Jamshidi S

更新日期：2016-11-01 00:00:00

abstract：:The human microbiome consists of all microorganisms occupying the skin, mucous membranes and intestinal tract of the human body. The contact of the mucosal immune system with the human microbiome is a balanced interplay between defence mechanisms of the immune system and symbiotic or pathogenic microbial factors, such...

journal_title：Oral diseases

authors： van der Meulen TA,Harmsen H,Bootsma H,Spijkervet F,Kroese F,Vissink A

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Prognosis of patients with head and neck squamous cell carcinoma (HNSCC) is still poor. Novel therapeutic approaches are of great interest to improve the effects of radiochemotherapy. We evaluated the effects of tyrosine kinase inhibitor neratinib on HNSCC cell lines CAL27, SCC25 and FaDu as a single agent an...

journal_title：Oral diseases

authors： Schneider S,Thurnher D,Kadletz L,Seemann R,Brunner M,Kotowski U,Schmid R,Lill C,Heiduschka G

更新日期：2016-11-01 00:00:00

abstract：:Salivary gland tumours represent a diverse range of tumours with many histological subtypes which occur in major and minor salivary glands. The management of these tumours is complex owing to their heterogeneity. Surgery together with radiotherapy and/or chemotherapy remains the treatment strategy for these tumours. T...

journal_title：Oral diseases

authors： Green B,Rahimi S,Brennan PA

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:We determined the correlation between saliva and serum for CA125 and leptin, and evaluated their clinical screening potential for parotid tumours. SUBJECTS AND METHODS:Serum, acid-stimulated bilateral parotid saliva and chewing-stimulated whole saliva were collected and measured the levels of CA125 and lept...

journal_title：Oral diseases

authors： Zhang KY,Liu CY,Hua L,Wang SL,Li J

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS:Male Wistar rats (n = 6-7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg k...

journal_title：Oral diseases

authors： de Barros Silva PG,de Oliveira CC,Brizeno L,Wong D,Lima Júnior R,Gonçalves RP,Sousa FB,Mota M,de Albuquerque Ribeiro R,Alves A

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the antitumor effects of fusion protein hGrB-TV of human granzyme B (hGrB) and truncated vascular endothelial growth factor (tVEGF) on human oral squamous cell carcinoma (OSCC) in vitro and in vivo. METHODS:The fusion protein hGrB-TV was expressed and purified from E. coli bacteria by affinity ch...

journal_title：Oral diseases

authors： Lv XZ,Zheng MY,Lin ZQ,Zhao M,Wang H,Zeng WS

更新日期：2016-10-01 00:00:00

abstract：:Dental teams have been involved with child protection for over 40 years. This brief review summarises their involvement in the detection of various types of child abuse and goes on to discuss the gap between the proportions of dental professionals who suspect child abuse or neglect in their paediatric patients and tho...

journal_title：Oral diseases

authors： Park CM,Welbury R

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate the prevalence of sleep bruxism in children in Japan, and its relationships with sleep-related factors and daytime problematic behavior. SUBJECTS AND METHODS:Guardians of 6023 children aged 2-12 years completed the Japanese Sleep Questionnaire. Multiple regression ...

journal_title：Oral diseases

authors： Tachibana M,Kato T,Kato-Nishimura K,Matsuzawa S,Mohri I,Taniike M

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:This article sets out to evaluate the prevalence and aetiopathogenesis of edentulism in patients on haemodialysis. SUBJECTS AND METHODS:The study group comprised 44 adult patients with end-stage renal disease (ESRD) on haemodialysis. A control group was formed of 44 individuals matched for age and sex and wi...

journal_title：Oral diseases

authors： Limeres J,Garcez JF,Marinho JS,Loureiro A,Diniz M,Diz P

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Candida-induced denture stomatitis is a common debilitating problem among denture wearers. Previously, we described the fabrication of a new denture material that released antifungal drugs when immersed in phosphate buffered saline. Here, we use more clinically relevant immersion conditions (human saliva; 37°...

journal_title：Oral diseases

authors： Malakhov A,Wen J,Zhang BX,Wang H,Geng H,Chen XD,Sun Y,Yeh CK

更新日期：2016-07-01 00:00:00

abstract：:Analysis of the prevalence and incidence of HIV infection globally reveal striking variances with regard to continent, country, region and gender. Of the global total of 33 million people infected with HIV, approximately 65% are in sub-Saharan African countries and 15% in South and South-East Asia with the remaining 2...

journal_title：Oral diseases

authors： Challacombe SJ

更新日期：2016-04-01 00:00:00

abstract：:Well into the fourth decade of the HIV/AIDS pandemic, we can look back on the early years, the initial discoveries, and the broad sweep of the progress of our understanding of the nature, causes, and significance of the oral lesions seen in those infected with the virus. Prominent among these is oral hairy leukoplakia...

journal_title：Oral diseases

authors： Greenspan JS,Greenspan D,Webster-Cyriaque J

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:We examined the content of YouTube(™) videos on mouth (oral) cancer and evaluated their usefulness in promoting early detection of oral cancer. MATERIALS AND METHODS:A systematic search of YouTube(™) for videos containing information on mouth cancer was conducted using the keywords 'mouth cancer' and 'oral ...

journal_title：Oral diseases

authors： Hassona Y,Taimeh D,Marahleh A,Scully C

更新日期：2016-04-01 00:00:00

abstract：:Most viral infections encountered in resource-rich countries are relatively trivial and transient with perhaps fever, malaise, myalgia, rash (exanthema) and sometimes mucosal manifestations (enanthema), including oral in some. However, the apparent benignity may be illusory as some viral infections have unexpected con...

journal_title：Oral diseases

authors： Scully C,Samaranayake LP

更新日期：2016-04-01 00:00:00

abstract：:As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the...

journal_title：Oral diseases

authors： Moyes DL,Islam A,Kohli A,Naglik JR

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Orofacial clefts (OFCs) are common birth defects that may impose a large burden on the health and psychosocioeconomic well-being of affected individuals and families. This study aims to identify qualitative factors that affect the quality of life (QOL) of family caregivers of children with OFCs. METHODS:A m...

journal_title：Oral diseases

authors： Awoyale T,Onajole AT,Ogunnowo BE,Adeyemo WL,Wanyonyi KL,Butali A

更新日期：2016-03-01 00:00:00